Saccharomyces cerevisiae chromosome XII
>YLR234W DNA Topoisomerase III, conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially, involved in telomere stability and regulation of mitotic recombination 
MKVLCVAEKNSIAKAVSQILGGGRSTSRDSGYMYVKNYDFMFSGFPFARNGANCEVTMTSVAGHLTGIDFSHDSHGWGKC
AIQELFDAPLNEIMNNNQKKIASNIKREARNADYLMIWTDCDREGEYIGWEIWQEAKRGNRLIQNDQVYRAVFSHLERQH
ILNAARNPSRLDMKSVHAVGTRIEIDLRAGVTFTRLLTETLRNKLRNQATMTKDGAKHRGGNKNDSQVVSYGTCQFPTLG
FVVDRFERIRNFVPEEFWYIQLVVENKDNGGTTTFQWDRGHLFDRLSVLTFYETCIETAGNVAQVVDLKSKPTTKYRPLP
LTTVELQKNCARYLRLNAKQSLDAAEKLYQKGFISYPRTETDTFPHAMDLKSLVEKQAQLDQLAAGGRTAWASYAASLLQ
PENTSNNNKFKFPRSGSHDDKAHPPIHPIVSLGPEANVSPVERRVYEYVARHFLACCSEDAKGQSMTLVLDWAVERFSAS
GLVVLERNFLDVYPWARWETTKQLPRLEMNALVDIAKAEMKAGTTAPPKPMTESELILLMDTNGIGTDATIAEHIDKIQV
RNYVRSEKVGKETYLQPTTLGVSLVHGFEAIGLEDSFAKPFQRREMEQDLKKICEGHASKTDVVKDIVEKYRKYWHKTNA
CKNTLLQVYDRVKASM



Supplementary options

Additional orf sequence data

See Genomic Environment

Search GenBank with PSI-Blast at NCBI

Search Complete Genomes DataBase with Blast at LBMGE

Search InterPro Database at LBMGE

Search CDD Database at LBMGE

Determine COG functional Category (microbial)

Determine COG functional Category (eukarial)


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GenBank id: 6323263                 
Gene name:  TOP3                                                                                        
COG:        L COG0550 Topoisomerase IA                                                                  
Taxon:      4932 
Lineage:    Eukaryota:                                                                                  
            Opisthokonta:                                                                               
            Fungi:                                                                                      
            Dikarya:                                                                                    
            Ascomycota:                                                                                 
            saccharomyceta:                                                                             
            Saccharomycotina:                                                                           
            Saccharomycetes:                                                                            
            Saccharomycetales:                                                                          
            Saccharomycetaceae:                                                                         
            Saccharomyces:                                                                              
            Saccharomyces cerevisiae                                                                    

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